Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0EP5O
|
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| Former ID |
DIB013874
|
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| Drug Name |
NS-377
|
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| Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Terminated | [1] | ||
| Company |
NeuroSearch A/S
|
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
c12c(C(=O)C(=O)N2)cc(c2c1CN(C2)CC)c1ccccc1
|
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| CAS Number |
CAS 160753-45-7
|
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| Target and Pathway | |||||
| Target(s) | Glutamate receptor AMPA subtype | Target Info | Antagonist | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005356) | ||||
| REF 2 | In vivo and in vitro evaluation of AMPA receptor antagonists in rat hippocampal neurones and cultured mouse cortical neurones. Eur J Pharmacol. 1998 Jul 24;353(2-3):159-67. | ||||
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