Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0EW4L
|
||||
| Former ID |
DAP000867
|
||||
| Drug Name |
Abatacept
|
||||
| Synonyms |
Orencia (TN)
|
||||
| Therapeutic Class |
Antirheumatic Agents
|
||||
| Company |
Bristol-Myers Squibb
|
||||
| CAS Number |
CAS 332348-12-6
|
||||
| SuperDrug ATC ID |
L04AA24
|
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| Target and Pathway | |||||
| Target(s) | T-lymphocyte activation antigen CD80 | Target Info | Binder | [537606] | |
| T-lymphocyte activation antigen CD86 | Target Info | Binder | [537606] | ||
| KEGG Pathway | Cell adhesion molecules (CAMs) | ||||
| Toll-like receptor signaling pathway | |||||
| Intestinal immune network for IgA production | |||||
| Type I diabetes mellitus | |||||
| Autoimmune thyroid disease | |||||
| Systemic lupus erythematosus | |||||
| Rheumatoid arthritis | |||||
| Allograft rejection | |||||
| Graft-versus-host disease | |||||
| Viral myocarditishsa04514:Cell adhesion molecules (CAMs) | |||||
| Transcriptional misregulation in cancer | |||||
| Viral myocarditis | |||||
| PANTHER Pathway | T cell activationP00053:T cell activation | ||||
| WikiPathways | Toll-like receptor signaling pathway | ||||
| Inflammatory Response Pathway | |||||
| PIP3 activates AKT signaling | |||||
| Primary Focal Segmental Glomerulosclerosis FSGS | |||||
| Allograft Rejection | |||||
| Costimulation by the CD28 family | |||||
| Regulation of toll-like receptor signaling pathwayWP75:Toll-like receptor signaling pathway | |||||
| IL-3 Signaling Pathway | |||||
| Regulation of toll-like receptor signaling pathway | |||||
| References | |||||
| Ref 536737 | Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54. | ||||
| Ref 541949 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6891). | ||||
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