Drug General Information
Drug ID
D0EX1W
Former ID
DIB009637
Drug Name
Ad-RTS-IL-12
Indication Melanoma [ICD9: 172; ICD10:C43] Phase 2 [549191]
Company
Ziopharm oncology
Target and Pathway
Target(s) Interleukin-12 ligand Target Info Modulator [544396]
KEGG Pathway Cytokine-cytokine receptor interaction
Toll-like receptor signaling pathway
RIG-I-like receptor signaling pathway
Jak-STAT signaling pathway
Type I diabetes mellitus
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Malaria
Toxoplasmosis
Amoebiasis
Tuberculosis
Measles
Influenza A
Herpes simplex infection
Inflammatory bowel disease (IBD)
Allograft rejection
WikiPathways Toll-like receptor signaling pathway
Aryl Hydrocarbon Receptor Pathway
Allograft Rejection
Regulation of toll-like receptor signaling pathway
References
Ref 549191Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800033476)
Ref 544396Interleukin 12: still a promising candidate for tumor immunotherapy?. Cancer Immunol Immunother. 2014; 63(5): 419-435.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.