| Drug General Information |
| Drug ID |
D0F3NH
|
| Former ID |
DIB012779
|
| Drug Name |
Balaglitazone
|
| Synonyms |
DRF-2593; NN-2344; DRF-2593-307; NNC-61-0645
|
| Drug Type |
Small molecular drug
|
| Indication |
Type 1 diabetes [ICD9: 250; ICD10:E10]
|
Phase 3 |
[1]
|
|---|
| Company |
Dr Reddy's Research Foundation
|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C20H17N3O4S
|
| Canonical SMILES |
n1(c(=O)c2c(nc1COc1ccc(CC3C(=O)NC(=O)S3)cc1)cccc2)C
|
| CAS Number |
CAS 199113-98-9
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Peroxisome proliferator activated receptor gamma |
Target Info |
Modulator |
|
|---|
|
KEGG Pathway
|
PPAR signaling pathway
|
|
AMPK signaling pathway
|
|
Osteoclast differentiation
|
|
Huntington's disease
|
|
Pathways in cancer
|
|
Transcriptional misregulation in cancer
|
|
Thyroid cancer
|
|
NetPath Pathway
|
IL1 Signaling Pathway
|
|
TGF_beta_Receptor Signaling Pathway
|
|
Leptin Signaling Pathway
|
|
PANTHER Pathway
|
CCKR signaling map ST
|
|
Pathway Interaction Database
|
Noncanonical Wnt signaling pathway
|
|
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
|
|
Signaling events mediated by HDAC Class I
|
|
RXR and RAR heterodimerization with other nuclear receptor
|
|
Regulation of retinoblastoma protein
|
|
Reactome
|
PPARA activates gene expression
|
|
Transcriptional regulation of white adipocyte differentiation
|
|
Nuclear Receptor transcription pathway
|
|
WikiPathways
|
Wnt Signaling Pathway Netpath
|
|
Nuclear Receptors in Lipid Metabolism and Toxicity
|
|
Differentiation of white and brown adipocyte
|
|
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
|
|
Transcriptional Regulation of White Adipocyte Differentiation
|
|
Adipogenesis
|
|
SREBP signalling
|
|
Nuclear Receptors
|
| References |
| REF 1 | ClinicalTrials.gov (NCT00515632) Efficacy and Safety of Treatment With Balaglitazone in Type 2 Diabetes Patients on Stable Insulin Therapy. U.S. National Institutes of Health. |
|---|
