Drug Information
Drug General Information | |||||
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Drug ID |
D0F4FK
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Former ID |
DIB020128
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Drug Name |
KB-R7943
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [467568] | ||
Structure |
Download2D MOL |
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Formula |
C17H21N3O6S2
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InChI |
InChI=1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4)
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InChIKey |
WGIKEBHIKKWJLG-UHFFFAOYSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
14782932, 24126784, 26759016, 44859801, 53787240, 53800721, 57373438, 79464357, 91746340, 135698241, 152079652, 152258706, 152344476, 160647542, 160821209, 162022899, 162249106, 163300006, 163374669, 163687832, 172844987, 175612701, 178101049, 184559922, 186014463, 204398567, 206251943, 208264937, 223393652, 227029080, 241182266, 242060122, 252215637, 252316128, 252433933, 252553669
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Target and Pathway | |||||
Target(s) | Short transient receptor potential channel 6 | Target Info | Blocker (channel blocker) | [543855] | |
TRP cation channel C5 | Target Info | Blocker (channel blocker) | [528962] | ||
Short transient receptor potential channel 3 | Target Info | Blocker (channel blocker) | [543852] | ||
References | |||||
Ref 528962 | The Na+/Ca2+ exchange inhibitor KB-R7943 potently blocks TRPC channels. Biochem Biophys Res Commun. 2007 Sep 14;361(1):230-6. Epub 2007 Jul 16. | ||||
Ref 543852 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 488). | ||||
Ref 543855 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 491). |
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