Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0F5AJ
|
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| Former ID |
DNC008410
|
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| Drug Name |
NORARISTEROMYCIN
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C10H13N5O3
|
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| Canonical SMILES |
C1C(C(C(C1O)O)O)N2C=NC3=C2N=CN=C3N
|
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| InChI |
1S/C10H13N5O3/c11-9-6-10(13-2-12-9)15(3-14-6)4-1-5(16)8(18)7(4)17/h2-5,7-8,16-18H,1H2,(H2,11,12,13)/t4-,5+,7+,8-/m1/s1
|
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| InChIKey |
VFKHECGAEJNAMV-HETMPLHPSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Adenosylhomocysteinase | Target Info | Inhibitor | [1] | |
| BioCyc Pathway | Superpathway of methionine degradation | ||||
| Methionine degradation | |||||
| Cysteine biosynthesis | |||||
| KEGG Pathway | Cysteine and methionine metabolism | ||||
| Metabolic pathways | |||||
| PathWhiz Pathway | Selenoamino Acid Metabolism | ||||
| Betaine Metabolism | |||||
| Methionine Metabolism | |||||
| WikiPathways | Metabolism of amino acids and derivatives | ||||
| Trans-sulfuration and one carbon metabolism | |||||
| One Carbon Metabolism | |||||
| Trans-sulfuration pathway | |||||
| Phase II conjugation | |||||
| Folate Metabolism | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2008 Apr 15;18(8):2615-8. Epub 2008 Mar 14.Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase. | ||||
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