Drug Information

Drug General Information
Drug ID
D0F5KN
Former ID
DNCL002256
Drug Name
99mTc-MIP-1405
Indication Prostate cancer [ICD9: 185; ICD10:C61] Phase 1 [523296]
Company
Molecular Insight Pharmaceuticals
Target and Pathway
Target(s) Glutamate carboxypeptidase II Target Info Modulator [532384]
KEGG Pathway Alanine, aspartate and glutamate metabolism
Metabolic pathways
Vitamin digestion and absorption
NetPath Pathway TCR Signaling Pathway
TNFalpha Signaling Pathway
Reactome Amino acid synthesis and interconversion (transamination)
WikiPathways One Carbon Metabolism
References
Ref 523296ClinicalTrials.gov (NCT01261754) A Study of 99mTc-MIP-1404 and 99mTc-MIP-1405 in Patients With Metastatic Prostate Adenocarcinoma and Healthy Volunteers. U.S. National Institutes of Health.
Ref 53238499mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer. J Nucl Med. 2013 Aug;54(8):1369-76.

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