Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0F6GV
|
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| Former ID |
DIB015514
|
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| Drug Name |
Perospirone
|
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| Synonyms |
Lullan; SM-9018
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| Drug Type |
Small molecular drug
|
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| Indication | Psychotic disorders [ICD9: 290-299; ICD10:F20-F29] | Approved | [1], [2] | ||
| Company |
Sumitomo Pharmaceuticals Co Ltd
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| Structure |
|
Download2D MOL |
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| Formula |
C23H30N4O2S
|
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| InChI |
InChI=1S/C23H30N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h3-4,9-10,17-18H,1-2,5-8,11-16H2/t17-,18+
|
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| InChIKey |
FBVFZWUMDDXLLG-HDICACEKSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-HT 2 receptor | Target Info | Modulator | [3], [2] | |
| KEGG Pathway | Calcium signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Gap junction | |||||
| Serotonergic synapse | |||||
| Inflammatory mediator regulation of TRP channels | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7556). | ||||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
| REF 3 | Pharmacological effects of zotepine and other antipsychotics on the central 5-HT2 receptors. Pharmacopsychiatry. 1993 Mar;26(2):53-8. | ||||
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