Drug General Information
Drug ID
D0F6KM
Former ID
DCL001199
Drug Name
ISIS-APOCIII
Drug Type
Antisense drug
Indication Inflammation; High triglycerides; Atherosclerosis; Metabolic syndrome [ICD9: 277.7, 414.0, 440; ICD10:E88.81, I70] Phase 1 [551052]
Company
ISIS Pharm
Target and Pathway
Target(s) mRNA of ApoC-III Target Info [551052]
KEGG Pathway PPAR signaling pathway
Reactome Chylomicron-mediated lipid transport
HDL-mediated lipid transport
Retinoid metabolism and transport
WikiPathways Statin Pathway
PPAR Alpha Pathway
Visual phototransduction
Lipid digestion, mobilization, and transport
References
Ref 551052Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).
Ref 551052Clinical pipeline report, company report or official report of ISIS Pharmaceuticals (2011).

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