Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0F7PZ
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| Former ID |
DIB002938
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| Drug Name |
PF-232798
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| Synonyms |
PF-00232798
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| Drug Type |
Small molecular drug
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| Indication | Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] | Phase 2 | [531280] | ||
| Company |
Pfizer Inc
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| Structure |
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Download2D MOL |
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| Formula |
C29H40FN5O2
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| Canonical SMILES |
c1(nc2c(CN(CC2)C(=O)C(C)C)n1[C@H]1C[C@@H]2N([C@@H](CC2)<br />C1)CC[C@H](NC(=O)C)c1cccc(c1)F)C
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | C-C chemokinereceptor type 5 | Target Info | Antagonist | [531280] | |
| Pathway Interaction Database | IL12-mediated signaling events | ||||
| References | |||||
| Ref 531280 | An imidazopiperidine series of CCR5 antagonists for the treatment of HIV: the discovery of N-{(1S)-1-(3-fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide (PF-232798). J Med Chem. 2011 Jan 13;54(1):67-77. | ||||
| Ref 531280 | An imidazopiperidine series of CCR5 antagonists for the treatment of HIV: the discovery of N-{(1S)-1-(3-fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide (PF-232798). J Med Chem. 2011 Jan 13;54(1):67-77. | ||||
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