Drug Information

Drug General Information
Drug ID
D0FC4R
Former ID
DNCL002842
Drug Name
CVX 096
Synonyms
PF-04856883
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 1 [523368]
Company
Pfizer
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Modulator [544390]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 523368ClinicalTrials.gov (NCT01301456) Single-Dose And Multiple-Dose Safety And Tolerability Study Of PF-04856883 In Type 2 Diabetic Adult Females. U.S. National Institutes of Health.
Ref 544390Chemically programmed antibodies. Trends Biotechnol. 2014 April; 32(4): 186-197.

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