Drug Information

Drug General Information
Drug ID
D0FD9M
Former ID
DIB019258
Drug Name
compound 15c
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531458]
Structure
Download
2D MOL
Formula
C26H38ClN3O5S
InChI
InChI=1S/C26H38ClN3O5S/c1-20-17-24(27)8-7-22(20)6-5-21-9-13-29(14-10-21)36(34,35)18-26(30(33)19-31)11-15-28(16-12-26)25(32)23-3-2-4-23/h7-8,17,19,21,23,33H,2-6,9-16,18H2,1H3
InChIKey
SIXCEPSXNLUZTE-UHFFFAOYSA-N
PubChem Compound ID
54585928
PubChem Substance ID
131284109, 131348468, 252166754
Target and Pathway
Target(s) Aggrecanase Target Info Inhibitor [531458]
Reactome Degradation of the extracellular matrix
O-glycosylation of TSR domain-containing proteins
WikiPathways Endochondral Ossification
Vitamin D Receptor Pathway
References
Ref 531458Orally active achiral N-hydroxyformamide inhibitors of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) for the treatment of osteoarthritis. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3301-6.
Ref 531458Orally active achiral N-hydroxyformamide inhibitors of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) for the treatment of osteoarthritis. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3301-6.

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