Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0FL5V
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| Former ID |
DAP001183
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| Drug Name |
Clobetasol
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| Synonyms |
Clobetasolum; Clofenazon; Clobecort Amex; Butavate (TN); Clobecort Amex (TN); Clobetasol (INN); Clobetasol [INN:BAN]; Clobetasolum [INN-Latin]; Clobex (TN); Dermatovate (TN); Dermovate (TN); Movate (TN); Olux (TN); Temovate (TN); Tenovate (TN); (11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; (8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; (9R,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; 17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one; 21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione; 21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
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| Drug Type |
Small molecular drug
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| Indication | Inflammatory and pruritic manifestations of moderate to severe corticosteroid-responsive dermatoses of the scalp [ICD10:L20-L30] | Approved | [551871] | ||
| Therapeutic Class |
Antiinflammatory Agents
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| Company |
Fougera Pharmaceuticals Inc
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| Structure |
|
Download2D MOL |
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| Formula |
C22H28ClFO4
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| Canonical SMILES |
CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)F)C
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| InChI |
1S/C22H28ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21?,22-/m0/s1
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| InChIKey |
FCSHDIVRCWTZOX-BZMSYRLXSA-N
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| CAS Number |
CAS 25122-46-7
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| SuperDrug ATC ID |
D07AD01
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| SuperDrug CAS ID |
cas=025122412
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| Target and Pathway | |||||
| Target(s) | Phospholipase A2 | Target Info | Inhibitor | [537809] | |
| BioCyc Pathway | Phospholipases | ||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | ||||
| WikiPathways | Glycerophospholipid biosynthesis | ||||
| References | |||||
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