Drug Information

Drug General Information
Drug ID
D0G1VS
Former ID
DNC004154
Drug Name
UK-78282
Drug Type
Small molecular drug
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Terminated [546612]
Structure
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2D MOL

3D MOL
Formula
C29H35NO2
Canonical SMILES
COC1=CC=C(C=C1)CCCN2CCC(CC2)COC(C3=CC=CC=C3)C4=CC=CC=C4
InChI
1S/C29H35NO2/c1-31-28-16-14-24(15-17-28)9-8-20-30-21-18-25(19-22-30)23-32-29(26-10-4-2-5-11-26)27-12-6-3-7-13-27/h2-7,10-17,25,29H,8-9,18-23H2,1H3
InChIKey
WRTXEGOLODUQIE-UHFFFAOYSA-N
PubChem Compound ID
656768
Target and Pathway
Target(s) Potassium voltage-gated channel subfamily A member 3 Target Info Inhibitor [526035]
Reactome Voltage gated Potassium channels
WikiPathways Potassium Channels
BDNF signaling pathway
References
Ref 546612Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009179)
Ref 526035J Med Chem. 2001 Apr 12;44(8):1249-56.Angular methoxy-substituted furo- and pyranoquinolinones as blockers of the voltage-gated potassium channel Kv1.3.

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