Drug General Information
Drug ID	D0G6BJ
Former ID	DNC011026
Drug Name	1-(3,4-DICHLOROPHENYL)-6-(METHOXYMETHYL)-3-AZABICYCLO[4.1.0]HEPTANE (ENANTIOMERIC MIX)
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530957]
Structure		Download 2D MOL 3D MOL
Formula	C14H17Cl2NO
PubChem Compound ID	24802842
Target and Pathway
Target(s)	Cytochrome P450 2D6	Target Info	Inhibitor	[530957]
	Cytochrome P450 3A4	Target Info	Inhibitor	[530957]
KEGG Pathway	Metabolism of xenobiotics by cytochrome P450
	Drug metabolism - cytochrome P450
	Serotonergic synapsehsa00140:Steroid hormone biosynthesis
	Linoleic acid metabolism
	Retinol metabolism
	Drug metabolism - other enzymes
	Metabolic pathways
	Bile secretion
	Chemical carcinogenesis
PathWhiz Pathway	Caffeine Metabolism
	Retinol Metabolism
Reactome	XenobioticsR-HSA-211981:Xenobiotics
	Aflatoxin activation and detoxification
WikiPathways	Metapathway biotransformation
	Tamoxifen metabolism
	Oxidation by Cytochrome P450
	Vitamin D Receptor Pathway
	Aripiprazole Metabolic Pathway
	Fatty Acid Omega Oxidation
	Codeine and Morphine MetabolismWP702:Metapathway biotransformation
	Aflatoxin B1 metabolism
	Estrogen metabolism
	Benzo(a)pyrene metabolism
	Tryptophan metabolism
	Nuclear Receptors in Lipid Metabolism and Toxicity
	Nuclear Receptors Meta-Pathway
	Farnesoid X Receptor Pathway
	Felbamate Metabolism
	Lidocaine metabolism
	Nifedipine Activity
	Colchicine Metabolic Pathway
	Irinotecan Pathway
	Drug Induction of Bile Acid Pathway
	Codeine and Morphine Metabolism
References
Ref 530957	J Med Chem. 2010 Jul 8;53(13):4989-5001.6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor.
Ref 530957	J Med Chem. 2010 Jul 8;53(13):4989-5001.6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane: a new potent and selective triple reuptake inhibitor.

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