Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0G6XT
|
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| Former ID |
DIB019749
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| Drug Name |
dioctanoylglycerol pyrophosphate
|
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| Synonyms |
DGPP 8:0
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [539932] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C19H38O11P2
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| InChI |
InChI=1S/C19H38O11P2/c1-3-5-7-9-11-13-18(20)27-15-17(16-28-32(25,26)30-31(22,23)24)29-19(21)14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H,25,26)(H2,22,23,24)/t17-/m1/s1
|
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| InChIKey |
MBDSUZSCJLRKPC-QGZVFWFLSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Lysophosphatidic acid receptor Edg-2 | Target Info | Antagonist | [526147] | |
| G protein coupled receptor 87 | Target Info | Antagonist | [529073] | ||
| P2RY10 | Target Info | Antagonist | [529462] | ||
| Lysophosphatidate-3 receptor | Target Info | Antagonist | [526147] | ||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | LPA receptor mediated eventslysophospholipid_pathway:LPA receptor mediated events | ||||
| References | |||||
| Ref 526147 | Short-chain phosphatidates are subtype-selective antagonists of lysophosphatidic acid receptors. Mol Pharmacol. 2001 Oct;60(4):776-84. | ||||
| Ref 529073 | The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor. Biochem Biophys Res Commun. 2007 Nov 23;363(3):861-6. Epub 2007 Sep 24. | ||||
| Ref 529462 | Identification of the orphan GPCR, P2Y(10) receptor as the sphingosine-1-phosphate and lysophosphatidic acid receptor. Biochem Biophys Res Commun. 2008 Jul 11;371(4):707-12. | ||||
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