Drug Information

Drug General Information
Drug ID
D0G8ZQ
Former ID
DIB008087
Drug Name
G17DT
Synonyms
Gastrimmune; Insegia
Drug Type
Antibody
Indication Gastric cancer [ICD9: 151; ICD10:C16] Phase 3 [524725]
Company
Receptor Biologix
Target and Pathway
Target(s) Gastrin Target Info [528685]
KEGG Pathway Gastric acid secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPK
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Gastric acid production
GPCR downstream signaling
References
Ref 524725ClinicalTrials.gov (NCT02118077) Sequential Trial of G17DT for the Treatment of Advanced Pancreatic Cancer. U.S. National Institutes of Health.
Ref 528685G17DT: an antigastrin immunogen for the treatment of gastrointestinal malignancy. Expert Opin Biol Ther. 2007 Mar;7(3):397-404.

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