TTD | Drug: D0GF4I

Drug General Information
Drug ID	D0GF4I
Former ID	DIB018629
Drug Name	4-thio-UTP
Synonyms	4-S-UTP; 4-thiouridine triphosphate
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539082]
Structure		Download 2D MOL
Formula	C9H15N2O14P3S
InChI	InChI=1S/C9H15N2O14P3S/c12-6-4(3-22-27(18,19)25-28(20,21)24-26(15,16)17)23-8(7(6)13)11-2-1-5(29)10-9(11)14/h1-2,4,6-8,12-13H,3H2,(H,18,19)(H,20,21)(H,10,14,29)(H2,15,16,17)/t4-,6-,7-,8-/m1/s1
InChIKey	GKVHYBAWZAYQDO-XVFCMESISA-N
PubChem Compound ID	3033941
PubChem Substance ID	15144453, 36077756, 57352810, 79808893, 111635397, 127968322, 131272457, 131344816, 135021475, 135651410, 226926681
Target and Pathway
Target(s)	P2Y purinoceptor 2	Target Info	Agonist	[528028]
KEGG Pathway	Neuroactive ligand-receptor interaction
KEGG Pathway	Inflammatory mediator regulation of TRP channels
NetPath Pathway	IL5 Signaling Pathway
Reactome	G alpha (q) signalling events
	P2Y receptors
	Surfactant metabolism
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539082	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1730).
Ref 528028	P2 receptors activated by uracil nucleotides--an update. Curr Med Chem. 2006;13(3):289-312.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information