Drug Information

Drug General Information
Drug ID
D0GT0Y
Former ID
DIB011232
Drug Name
MN-246
Synonyms
Incontinence therapy, MediciNova; TT-138; Beta 3 adrenoceptor agonist (incontinence), MediciNova
Indication Urinary incontinence [ICD9: 788.3; ICD10:N39.3, N39.4, R32] Discontinued in Phase 1 [548176]
Company
Mitsubishi Pharma Corp
Target and Pathway
Target(s) Beta-3 adrenergic receptor Target Info Agonist [550845]
KEGG Pathway Calcium signaling pathway
cGMP-PKG signaling pathway
Neuroactive ligand-receptor interaction
Endocytosis
Salivary secretion
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Beta3 adrenergic receptor signaling pathway
Reactome Adrenoceptors
G alpha (s) signalling events
WikiPathways Monoamine GPCRs
Calcium Regulation in the Cardiac Cell
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 548176Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800022773)
Ref 550845CA patent application no. 630818, Pharmaceutical composition for prevention or treatment of neurogenic pain.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.