Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0GV0Q
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| Former ID |
DIB007164
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| Drug Name |
BMY-43748
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| Synonyms |
7-[3(S)-Aminopyrrolidin-1-yl]-1-(2,4-difluorophenyl)-6-fluoro-5-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylicacid
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| Drug Type |
Small molecular drug
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| Indication | Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] | Phase 1 | [1] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C22H20ClF3N4O3
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| Canonical SMILES |
CC1=C2C(=O)C(=CN(C2=NC(=C1F)N3CC4CCC3CN4)C5=C(C=C(C=C5)<br />F)F)C(=O)O.Cl
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| InChI |
1S/C22H19F3N4O3.ClH/c1-10-17-19(30)14(22(31)32)9-29(16-5-2-11(23)6-15(16)24)20(17)27-21(18(10)25)28-8-12-3-4-13(28)7-26-12;/h2,5-6,9,12-13,26H,3-4,7-8H2,1H3,(H,31,32);1H
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| InChIKey |
WZPJEHNEEUMGGA-UHFFFAOYSA-N
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| CAS Number |
CAS 132195-65-4
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | DNA topoisomerase II | Target Info | Modulator | [1], [2] | |
| References | |||||
| REF 1 | Comparative metabolism of tosufloxacin and BMY 43748 in hepatocytes from rat, dog, monkey and man. Toxicol In Vitro. 1993 Jul;7(4):499-503. | ||||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | ||||
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