Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0GY5Z
|
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| Former ID |
DAP000843
|
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| Drug Name |
Aspirin
|
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| Drug Type |
Small molecular drug
|
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| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Approved | [1], [2] | ||
| Cardiovascular disorder [ICD10:I00-I99] | Phase 3 | [1], [3], [4] | |||
| Therapeutic Class |
Analgesics
|
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| Company |
Bayer Pharmaceuticals Corporation
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C9H8O4
|
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| InChIKey |
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
|
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| CAS Number |
CAS 50-78-2
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
4594, 87798, 476106, 602429, 829042, 832958, 840714, 3135921, 5261264, 7847177, 7885805, 7978731, 8143164, 8149208, 8151516, 10524572, 11110749, 11335730, 11360969, 11364139, 11364685, 11366701, 11367247, 11369263, 11369809, 11372248, 11372850, 11373537, 11375409, 11377425, 11377972, 11406615, 11461941, 11485574, 11489715, 11491110, 11491914, 11495059, 15195166, 17389202, 17390036, 17404602, 24278218, 24714725, 24890623, 24890723, 24891140, 26611613, 26679412, 26717767
|
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| ChEBI ID |
ChEBI:15365
|
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| SuperDrug ATC ID |
A01AD05; B01AC06; N02BA01
|
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| SuperDrug CAS ID |
cas=000050782
|
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| Drug Resistance Mutation (DRM) | |||||
| DRM | DRM Info | ||||
| Target and Pathway | |||||
| Target(s) | Cyclooxygenase | Target Info | Inhibitor | [5] | |
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4139). | ||||
| REF 2 | Emerging drugs in peripheral arterial disease. Expert Opin Emerg Drugs. 2006 Mar;11(1):75-90. | ||||
| REF 3 | The mechanism of action of aspirin. Thromb Res. 2003 Jun 15;110(5-6):255-8. | ||||
| REF 4 | Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971 Jun 23;231(25):232-5. | ||||
| REF 5 | Cyclooxygenase inhibitors: instrumental drugs to understand cardiovascular homeostasis and arterial thrombosis. Cardiovasc Hematol Disord Drug Targets. 2008 Dec;8(4):268-77. | ||||
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