Drug General Information
Drug ID	D0H1GU
Former ID	DNC002683
Drug Name	Double Oxidized Cysteine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551393]
Structure		Download 2D MOL 3D MOL
Formula	C3H6NO4S
PubChem Compound ID	46936210
Target and Pathway
Target(s)	Alpha-glucosidase	Target Info	Inhibitor	[551393]
	mRNA of Protein tyrosine phosphatase-1B	Target Info	Inhibitor	[551393]
	Maltase-glucoamylase, intestinal	Target Info	Inhibitor	[551393]
	M-phase inducer phosphatase 2	Target Info	Inhibitor	[551393]
	Cell division protein kinase 2	Target Info	Inhibitor	[551393]
	Beta crystallin B1	Target Info	Inhibitor	[551393]
	Prolyl endopeptidase	Target Info	Inhibitor	[551393]
	Peptide deformylase	Target Info	Inhibitor	[551393]
KEGG Pathway	Adherens junction
	Insulin signaling pathwayhsa00052:Galactose metabolism
	Starch and sucrose metabolism
	Metabolic pathways
	Carbohydrate digestion and absorptionhsa04010:MAPK signaling pathway
	Cell cycle
	Progesterone-mediated oocyte maturation
	MicroRNAs in cancerhsa04068:FoxO signaling pathway
	Oocyte meiosis
	p53 signaling pathway
	PI3K-Akt signaling pathway
	Hepatitis B
	Measles
	Herpes simplex infection
	Epstein-Barr virus infection
	Pathways in cancer
	Viral carcinogenesis
	Prostate cancer
	Small cell lung cancerhsa04614:Renin-angiotensin system
NetPath Pathway	FSH Signaling PathwayNetPath_14:IL2 Signaling Pathway
	TGF_beta_Receptor Signaling Pathway
	Wnt Signaling PathwayNetPath_11:TCR Signaling Pathway
PANTHER Pathway	Cadherin signaling pathwayP00059:p53 pathway
	p53 pathway feedback loops 2P04395:Vasopressin synthesis
Pathway Interaction Database	Insulin Pathway
	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
	Signaling events mediated by PTP1B
	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
	Signaling events mediated by TCPTP
	IGF1 pathway
	EGF receptor (ErbB1) signaling pathway
	Posttranslational regulation of adherens junction stability and dissassembly
	PDGFR-beta signaling pathway
	N-cadherin signaling eventsplk1_pathway:PLK1 signaling events
	FOXM1 transcription factor network
	p38 signaling mediated by MAPKAP kinases
	Aurora A signalingsmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
	Signaling events mediated by PRL
	p73 transcription factor network
	E2F transcription factor network
	ATR signaling pathway
	mTOR signaling pathway
	IL2-mediated signaling events
	FoxO family signaling
	BARD1 signaling events
	p53 pathway
	Regulation of retinoblastoma protein
PathWhiz Pathway	Starch and Sucrose Metabolism
Reactome	Integrin alphaIIb beta3 signaling
	Regulation of IFNG signaling
	Regulation of IFNA signaling
	Growth hormone receptor signalingR-HSA-157881:Cyclin B2 mediated events
	Cyclin A/B1 associated events during G2/M transition
	Cyclin A:Cdk2-associated events at S phase entryR-HSA-1538133:G0 and Early G1
	Activation of ATR in response to replication stress
	Regulation of APC/C activators between G1/S and early anaphase
	SCF(Skp2)-mediated degradation of p27/p21
	Senescence-Associated Secretory Phenotype (SASP)
	DNA Damage/Telomere Stress Induced Senescence
	Processing of DNA double-strand break ends
	G2 Phase
	Orc1 removal from chromatin
	Cyclin E associated events during G1/S transition
	p53-Dependent G1 DNA Damage Response
	Cyclin A:Cdk2-associated events at S phase entry
	Meiotic recombination
	Factors involved in megakaryocyte development and platelet production
WikiPathways	Insulin Signaling
	Growth hormone receptor signaling
	Leptin signaling pathway
	Interferon gamma signaling
	Interferon alpha/beta signaling
	Integrin alphaIIb beta3 signalingWP1848:Metabolism of carbohydratesWP615:Senescence and Autophagy in Cancer
	MAPK Signaling Pathway
	Retinoblastoma (RB) in Cancer
	Prostate Cancer
	Integrated Breast Cancer Pathway
	Integrated Cancer pathway
	Mitotic G2-G2/M phases
	Cell CycleWP707:DNA Damage Response
	ID signaling pathway
	DNA Replication
	G1 to S cell cycle control
	M/G1 Transition
	S Phase
	Meiotic Recombination
	Aryl Hydrocarbon Receptor
	ATM Signaling Pathway
	Spinal Cord Injury
	Integrated Pancreatic Cancer Pathway
	Oncostatin M Signaling Pathway
	Signaling Pathways in Glioblastoma
	TSH signaling pathway
	Synthesis of DNA
	Regulation of DNA replication
	Mitotic G1-G1/S phases
	Factors involved in megakaryocyte development and platelet production
	Cell Cycle
	APC/C-mediated degradation of cell cycle proteins
	Cell Cycle Checkpoints
	miRNA Regulation of DNA Damage Response
References
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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