Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0H1YE
|
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| Former ID |
DIB014253
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| Drug Name |
BE-22179
|
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| Indication | Leukemia [ICD9: 208.9; ICD10:C90-C95] | Terminated | [1] | ||
| Company |
MSD Japan
|
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| Structure |
|
Download2D MOL |
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| Formula |
C46H48N10O12S4
|
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| Canonical SMILES |
C1(=O)N(C(=C)C(=O)SCC(C(=O)NCC(=O)N(C2C(=O)N(C(=C)C(=O)<br />SCC(C(=O)NCC(=O)N(C1CSSC2)C)NC(=O)c1nc2c(cc1O)cccc2)C)C<br />)NC(=O)c1nc2c(cc1O)cccc2)C
|
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| CAS Number |
CAS 147816-33-9
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | DNA topoisomerase II | Target Info | Modulator | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004286) | ||||
| REF 2 | A new topoisomerase II inhibitor, BE-22179, produced by a streptomycete. I. Producing strain, fermentation, isolation and biological activity. J Antibiot (Tokyo). 1994 Feb;47(2):129-35. | ||||
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