Drug Information

Drug General Information
Drug ID
D0H2MA
Former ID
DIB019019
Drug Name
brilliant blue G
Drug Type
Small molecular drug
Indication Discovery agent Investigative [467492]
Structure
Download
2D MOL
Formula
C47H48N3NaO7S2
InChI
InChI=1S/C47H49N3O7S2.Na/c1-6-49(31-35-12-24-43(25-13-35)58(51,52)53)40-20-26-45(33(4)28-40)47(37-14-16-38(17-15-37)48-39-18-22-42(23-19-39)57-8-3)46-27-21-41(29-34(46)5)50(7-2)32-36-10-9-11-44(30-36)59(54,55)56;/h9-30H,6-8,31-32H2,1-5H3,(H2,51,52,53,54,55,56);/q;+1/p-1
InChIKey
NIVDAYXBPZLBDP-UHFFFAOYSA-M
PubChem Compound ID
73755082
PubChem Substance ID
178100968
Target and Pathway
Target(s) P2X purinoceptor 7 Target Info Antagonist [525800]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome The NLRP3 inflammasome
WikiPathways Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
References
Ref 467492(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4147).
Ref 525800Brilliant blue G selectively blocks ATP-gated rat P2X(7) receptors. Mol Pharmacol. 2000 Jul;58(1):82-8.

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