Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0H2MF
|
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| Former ID |
DNC010894
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| Drug Name |
PF-02367982
|
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| Drug Type |
Small molecular drug
|
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| Indication | Endometriosis [ICD9: 617; ICD10:N80] | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H21N3O2
|
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| Canonical SMILES |
CNC(=O)CN1C=C(C(=C1C2CC2)OC3=CC=C(C=C3)C#N)C4CC4
|
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| InChI |
1S/C20H21N3O2/c1-22-18(24)12-23-11-17(14-4-5-14)20(19(23)15-6-7-15)25-16-8-2-13(10-21)3-9-16/h2-3,8-9,11,14-15H,4-7,12H2,1H3,(H,22,24)
|
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| InChIKey |
AALHNBNOUAEYHF-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Progesterone receptor | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Oocyte meiosis | ||||
| Progesterone-mediated oocyte maturation | |||||
| Pathway Interaction Database | Cellular roles of Anthrax toxin | ||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Nuclear Receptor transcription pathway | |||||
| WikiPathways | Ovarian Infertility Genes | ||||
| Signaling by ERBB4 | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2010 Jun 1;20(11):3384-6. Epub 2010 Apr 13.Optimisation of a pyrazole series of progesterone antagonists; Part 1. | ||||
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