Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0H3UW
|
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| Former ID |
DIB018006
|
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| Drug Name |
compound 1
|
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| Drug Type |
Small molecular drug
|
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| Formula |
C26H24N6O7
|
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| InChI |
InChI=1S/C26H24N6O7/c27-23(28)12-2-3-18-19(8-12)32-24(31-18)17-7-13(14(25(37)38)9-21(34)35)6-16(22(17)36)15-5-11(1-4-20(15)33)10-30-26(29)39/h1-8,14,31-33H,9-10H2,(H3,27,28)(H,34,35)(H,37,38)(H3,29,30,39)/b24-17+
|
||||
| InChIKey |
VPCHMCAFZYYMSK-JJIBRWJFSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Coagulation factor VII | Target Info | Inhibitor | [528175] | |
| KEGG Pathway | Complement and coagulation cascades | ||||
| PANTHER Pathway | Angiogenesis | ||||
| Blood coagulation | |||||
| PathWhiz Pathway | Coagulation | ||||
| Reactome | BMAL1:CLOCK,NPAS2 activates circadian gene expression | ||||
| Extrinsic Pathway of Fibrin Clot Formation | |||||
| Gamma-carboxylation of protein precursors | |||||
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
| References | |||||
| Ref 528175 | Efforts toward oral bioavailability in factor VIIa inhibitors. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3829-32. Epub 2006 May 2. | ||||
| Ref 541676 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6552). | ||||
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