Drug Information

Drug General Information
Drug ID
D0H4GB
Former ID
DPR000027
Drug Name
CB1 antagonist, Bayer
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Preclinical [536122]
Company
Bayer
Structure
Download
2D MOL

3D MOL
Formula
C14H10Cl2NO2-
Canonical SMILES
CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)[O-])Cl
InChI
1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19)/p-1
InChIKey
SBDNJUWAMKYJOX-UHFFFAOYSA-M
CAS Number
CAS 168273-06-1
PubChem Compound ID
4036
PubChem Substance ID
4906244, 12016107, 22391420, 26751537, 29223147, 46487937, 49698868, 50104118, 50104119, 51010207, 90341585, 103925146, 104305243, 124749947, 126407770, 134339503, 163218459, 169350735, 170474292, 223454453
SuperDrug ATC ID
M01AG04
SuperDrug CAS ID
cas=000644622
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Antagonist [536122]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.
Ref 536122Emerging drugs for obesity: linking novel biological mechanisms to pharmaceutical pipelines. Expert Opin Emerg Drugs. 2005 Aug;10(3):643-60.

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