Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0H4RV
|
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| Former ID |
DIB000074
|
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| Drug Name |
NDC-1022
|
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| Synonyms |
Estrogen receptor beta agonists (cancer); NDC-1022; NDC-1308; Estrogen receptor beta agonists (cancer), Endece
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| Indication | Cancer [ICD9: 140-229; ICD10:C00-C96] | Investigative | [1] | ||
| Company |
Endece LLC
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
c1c(cc2c(c1)[C@@H]1[C@@H](C[C@H]2CCCCCCOC)[C@H]2[C@](CC<br />1)([C@H](CC2)O)C)O
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| Target and Pathway | |||||
| Target(s) | Estrogen receptor beta | Target Info | Agonist | [1] | |
| KEGG Pathway | Estrogen signaling pathway | ||||
| Prolactin signaling pathway | |||||
| Pathway Interaction Database | Plasma membrane estrogen receptor signaling | ||||
| Validated nuclear estrogen receptor beta network | |||||
| Validated nuclear estrogen receptor alpha network | |||||
| Reactome | Nuclear Receptor transcription pathway | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Ovarian Infertility Genes | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 621). | ||||
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