Drug Information

Drug General Information
Drug ID
D0H4RV
Former ID
DIB000074
Drug Name
NDC-1022
Synonyms
Estrogen receptor beta agonists (cancer); NDC-1022; NDC-1308; Estrogen receptor beta agonists (cancer), Endece
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [543899]
Company
Endece LLC
Structure
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2D MOL

3D MOL
Canonical SMILES
c1c(cc2c(c1)[C@@H]1[C@@H](C[C@H]2CCCCCCOC)[C@H]2[C@](CC<br />1)([C@H](CC2)O)C)O
Target and Pathway
Target(s) Estrogen receptor beta Target Info Agonist [543899]
KEGG Pathway Estrogen signaling pathway
Prolactin signaling pathway
Pathway Interaction Database Plasma membrane estrogen receptor signaling
Validated nuclear estrogen receptor beta network
Validated nuclear estrogen receptor alpha network
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Ovarian Infertility Genes
Integrated Pancreatic Cancer Pathway
Nuclear Receptors
References
Ref 543899(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 621).
Ref 543899(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 621).

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