TTD | Drug: D0HR8H

Drug General Information
Drug ID	D0HR8H
Former ID	DNC002828
Drug Name	(5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551393]
Structure		Download 2D MOL 3D MOL
Formula	C4H5IN2O2
Canonical SMILES	C1C(C(=O)NC(=O)N1)I
InChI	1S/C4H5IN2O2/c5-2-1-6-4(9)7-3(2)8/h2H,1H2,(H2,6,7,8,9)/t2-/m0/s1
InChIKey	YGKCTZPSAOUUMT-REOHCLBHSA-N
PubChem Compound ID	5288605
PubChem Substance ID	7888318, 39320971, 51024627, 81059697, 113872375, 137264978, 230257564, 247624155
Target and Pathway
Target(s)	Dihydropyrimidine dehydrogenase [NADP+]	Target Info	Inhibitor	[551393]
BioCyc Pathway	Pyrimidine ribonucleosides degradation
	Thymine degradation
	Uracil degradation
KEGG Pathway	Pyrimidine metabolism
	beta-Alanine metabolism
	Pantothenate and CoA biosynthesis
	Drug metabolism - other enzymes
	Metabolic pathways
PANTHER Pathway	Pyrimidine Metabolism
PathWhiz Pathway	Beta-Alanine Metabolism
PathWhiz Pathway	Pyrimidine Metabolism
WikiPathways	Metabolism of nucleotides
WikiPathways	Fluoropyrimidine Activity
References
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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Drug Information