Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0HX0D
|
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| Former ID |
DNC001447
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| Drug Name |
Tin protoporphyrin
|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [535305] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C34H32N4O4Sn
|
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| Canonical SMILES |
CC1=C(C2=CC3=C(C(=C([N-]3)C=C4C(=C(C(=CC5=C(C(=C([N-]5)<br />C=C1[N-]2)C=C)C)[N-]4)C=C)C)C)CCC(=O)O)CCC(=O)O.[Sn+4]
|
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| InChI |
1S/C34H32N4O4.Sn/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42);/q-4;+4/b25-13-,26-13?,27-14?,28-15-,29-14-,30-15?,31-16?,32-16-;
|
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| InChIKey |
VWEYNEFKXXWVHZ-QPPPNFCJSA-N
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| CAS Number |
CAS 12397-01-2
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Heme oxygenase | Target Info | Inhibitor | [535305] | |
| BioCyc Pathway | Heme degradation | ||||
| Pathway Interaction Database | Validated transcriptional targets of AP1 family members Fra1 and Fra2 | ||||
| HIF-1-alpha transcription factor network | |||||
| PathWhiz Pathway | Porphyrin Metabolism | ||||
| Reactome | Iron uptake and transport | ||||
| WikiPathways | Oxidative Stress | ||||
| Transcriptional activation by NRF2 | |||||
| NRF2 pathway | |||||
| Nuclear Receptors Meta-Pathway | |||||
| miR-targeted genes in squamous cell - TarBase | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| miR-targeted genes in leukocytes - TarBase | |||||
| miR-targeted genes in epithelium - TarBase | |||||
| References | |||||
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