TTD | Drug: D0I0TD

Drug General Information
Drug ID	D0I0TD
Former ID	DIB008777
Drug Name	AZM-134
Synonyms	AZM-133; GLP-1 mimetics, Alizyme; Glucagon-like peptide-1 mimetics, Alizyme
Indication	Type 2 diabetes [ICD9: 250; ICD10:E11]		Terminated	[546517]
Company	Alizyme plc
Target and Pathway
Target(s)	Glucagon-like peptide 1 receptor	Target Info	Modulator	[550154]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Insulin secretion
Reactome	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
	G alpha (s) signalling events
	Glucagon-type ligand receptors
WikiPathways	GPCRs, Class B Secretin-like
	Integration of energy metabolism
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 546517	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008696)
Ref 550154	US patent application no. 2011,0171,312, Modified therapeutic peptides, methods of their preparation and use.

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Drug Information