Drug Information

Drug General Information
Drug ID
D0I1BX
Former ID
DIB011942
Drug Name
CGS-32359
Synonyms
C5aRAD
Indication Inflammatory disease [ICD9: 140-229, 147, 173, 573.3, 710-719; ICD10:C11, C44, K75.9, M00-M25] Terminated [546756]
Company
Novartis AG
CAS Number
CAS 209856-24-6
Target and Pathway
Target(s) Complement C5 Target Info Inhibitor [544090]
KEGG Pathway Complement and coagulation cascades
Prion diseases
Pertussis
Staphylococcus aureus infection
Herpes simplex infection
Systemic lupus erythematosus
Reactome Activation of C3 and C5
Peptide ligand-binding receptors
G alpha (i) signalling events
Regulation of Complement cascade
WikiPathways Complement Activation, Classical Pathway
Human Complement System
Spinal Cord Injury
Allograft Rejection
GPCR ligand binding
GPCR downstream signaling
Complement cascade
References
Ref 546756Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010131)
Ref 544090Anticomplement therapy. Biologics. 2008 December; 2(4): 671-685.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.