Drug Information

Drug General Information
Drug ID
D0I4OI
Former ID
DCL000066
Drug Name
BF-Derm1
Drug Type
Small molecular drug
Indication Skin infections [ICD9: 680-709; ICD10:L00-L99] Phase 2 [547936]
Company
Biofrontera
Structure
Download
2D MOL

3D MOL
Formula
C27H21ClFN3O2
Canonical SMILES
CC1=C(C=C(C=C1)F)C(=O)NC2=CC(=C(C=C2)C(=O)N3CC4=CC=CN4C<br />C5=CC=CC=C53)Cl
InChI
1S/C27H21ClFN3O2/c1-17-8-9-19(29)13-23(17)26(33)30-20-10-11-22(24(28)14-20)27(34)32-16-21-6-4-12-31(21)15-18-5-2-3-7-25(18)32/h2-14H,15-16H2,1H3,(H,30,33)
InChIKey
PPHTXRNHTVLQED-UHFFFAOYSA-N
PubChem Compound ID
172997
PubChem Substance ID
7980888, 10257813, 14883146, 33497450, 47206571, 51007980, 57352187, 85210111, 103230841, 103960062, 113473195, 125299293, 128948849, 134338769, 134339327, 134340482, 135127191, 135650528, 137263757, 137267623, 141986343, 164228268, 164761614, 176225592, 179150049, 198968309, 202821333, 215780791, 223532830, 223661309, 224998594, 227838647, 251971379
Target and Pathway
Target(s) Histidine decarboxylase Target Info Inhibitor [550362]
KEGG Pathway Histidine metabolism
Metabolic pathways
PANTHER Pathway Histamine synthesis
CCKR signaling map ST
PathWhiz Pathway Histidine Metabolism
WikiPathways Biogenic Amine Synthesis
Metabolism of amino acids and derivatives
References
Ref 547936Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020550)
Ref 550362Clinical pipeline report, company report or official report of Biofrontera (2009).

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