Drug Information
Drug General Information | |||||
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Drug ID |
D0I6IB
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Former ID |
DAP000736
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Drug Name |
Tenoxicam
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Synonyms |
Artriunic; Liman; Mobiflex; Reutenox; Tenoxicamum; Tilcotil; Apotex brand of tenoxicam; Novag brand of tenoxicam; Novopharm brand of tenoxicam; Roche brand of tenoxicam; Solvay brand of tenoxicam; Apo-Tenoxicam; Mobiflex (TN); Novo-Tenoxicam; Ro 12-0068; Ro-120068; Tenoxicamum [INN-Latin]; Tilcotil (TN); Ro 12-0068/000; Ro-12-0068; Tenoxicam (JAN/USAN/INN); Tenoxicam [USAN:BAN:INN:JAN]; (3E)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one; (3Z)-3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one; 2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide; 3-[hydroxy-(pyridin-2-ylamino)methylidene]-2-methyl-1,1-dioxothieno[2,3-e]thiazin-4-one; 4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE; 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide1,1-dioxide; 4-Hydroxy-2-methyl-N-2-pyridyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide; 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
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Drug Type |
Small molecular drug
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Indication | Rheumatold arthritis; Osteoarthritis [ICD9: 714, 715; ICD10:M05-M06, M15-M19, M47] | Approved | [1], [2], [3] | ||
Therapeutic Class |
Antiinflammatory Agents
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Company |
Roche Laboratories Inc
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Structure |
Download2D MOL |
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Formula |
C13H11N3O4S2
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CAS Number |
CAS 59804-37-4
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PubChem Compound ID | |||||
SuperDrug ATC ID |
M01AC02
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SuperDrug CAS ID |
cas=059804374
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Target and Pathway | |||||
Target(s) | Prostaglandin G/H synthase 2 | Target Info | Inhibitor | [4], [5] | |
BioCyc Pathway | Aspirin-triggered lipoxin biosynthesis | ||||
Aspirin triggered resolvin D biosynthesis | |||||
C20 prostanoid biosynthesis | |||||
Aspirin triggered resolvin E biosynthesis | |||||
KEGG Pathway | Arachidonic acid metabolism | ||||
Metabolic pathways | |||||
NF-kappa B signaling pathway | |||||
VEGF signaling pathway | |||||
TNF signaling pathway | |||||
Retrograde endocannabinoid signaling | |||||
Serotonergic synapse | |||||
Ovarian steroidogenesis | |||||
Oxytocin signaling pathway | |||||
Regulation of lipolysis in adipocytes | |||||
Leishmaniasis | |||||
Pathways in cancer | |||||
Chemical carcinogenesis | |||||
MicroRNAs in cancer | |||||
Small cell lung cancer | |||||
NetPath Pathway | IL1 Signaling Pathway | ||||
TSH Signaling Pathway | |||||
IL4 Signaling Pathway | |||||
TGF_beta_Receptor Signaling Pathway | |||||
IL5 Signaling Pathway | |||||
PANTHER Pathway | Endothelin signaling pathway | ||||
Inflammation mediated by chemokine and cytokine signaling pathway | |||||
Toll receptor signaling pathway | |||||
CCKR signaling map ST | |||||
Pathway Interaction Database | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | ||||
S1P1 pathway | |||||
C-MYB transcription factor network | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
Calcium signaling in the CD4+ TCR pathway | |||||
PathWhiz Pathway | Arachidonic Acid Metabolism | ||||
WikiPathways | Prostaglandin Synthesis and Regulation | ||||
Arachidonic acid metabolism | |||||
Aryl Hydrocarbon Receptor | |||||
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | |||||
Spinal Cord Injury | |||||
Integrated Pancreatic Cancer Pathway | |||||
Eicosanoid Synthesis | |||||
Selenium Micronutrient Network | |||||
References | |||||
REF 1 | Tenoxicam exerts a neuroprotective action after cerebral ischemia in rats. Neurochem Res. 2005 Jan;30(1):39-46. | ||||
REF 2 | In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis. Ann Clin Lab Sci. 2005 Spring;35(2):137-43. | ||||
REF 3 | Drug information of Tenoxicam, 2008. eduDrugs. | ||||
REF 4 | A randomized crossover trial of tenoxicam compared with rofecoxib for postoperative dental pain control. Anaesth Intensive Care. 2004 Dec;32(6):770-4. | ||||
REF 5 | The use and safety profile of non-steroidal antiinflammatory drugs among Turkish patients with osteoarthritis. Turk J Gastroenterol. 2005 Sep;16(3):138-42. | ||||
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