Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0I7DH
|
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| Former ID |
DNC007839
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| Drug Name |
(E)-1-(4-heptylphenyl)but-2-en-1-one
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C17H24O
|
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| Canonical SMILES |
CCCCCCCC1=CC=C(C=C1)C(=O)C=CC
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| InChI |
1S/C17H24O/c1-3-5-6-7-8-10-15-11-13-16(14-12-15)17(18)9-4-2/h4,9,11-14H,3,5-8,10H2,1-2H3/b9-4+
|
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| InChIKey |
LCSOCUYXJADQCV-RUDMXATFSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Thyroid hormone receptor beta-1 | Target Info | Inhibitor | [1] | |
| Thyroid hormone receptor alpha | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Thyroid hormone signaling pathwayhsa04080:Neuroactive ligand-receptor interaction | |||||
| Thyroid hormone signaling pathway | |||||
| Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptorrxr_vdr_pathway:RXR and RAR heterodimerization with other nuclear receptor | ||||
| Reactome | Nuclear Receptor transcription pathwayR-HSA-383280:Nuclear Receptor transcription pathway | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Hematopoietic Stem Cell Differentiation | |||||
| Nuclear ReceptorsWP474:Endochondral Ossification | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | J Med Chem. 2007 Nov 1;50(22):5269-80. Epub 2007 Oct 5.Inhibitors of the interaction of a thyroid hormone receptor and coactivators: preliminary structure-activity relationships. | ||||
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