Drug Information

Drug General Information
Drug ID
D0IN8Z
Former ID
DNCL003814
Drug Name
LY2928057
Indication Anemia [ICD9: 280-285; ICD10:D50-D64] Phase 1 [523421]
Company
Lilly
Target and Pathway
Target(s) Ferroportin Target Info Modulator [544308]
KEGG Pathway Mineral absorption
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Reactome Iron uptake and transport
WikiPathways Iron uptake and transport
Iron metabolism in placenta
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 523421ClinicalTrials.gov (NCT01330953) A First Human Study of a Ferroportin Antibody. U.S. National Institutes of Health.
Ref 544308Targeting the Hepcidin-Ferroportin Axis to Develop New Treatment Strategies for Anemia of Chronic Disease and Anemia of Inflammation. Am J Hematol. 2012 April; 87(4): 392-400.

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