Drug General Information
Drug ID
D0IX0N
Former ID
DNC011569
Drug Name
N*1*-(5-Methyl-2-nitro-phenyl)-butane-1,4-diamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534663]
Structure
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2D MOL

3D MOL

Formula
C11H17N3O2
Canonical SMILES
CC1=CC(=C(C=C1)[N+](=O)[O-])NCCCCN
InChI
1S/C11H17N3O2/c1-9-4-5-11(14(15)16)10(8-9)13-7-3-2-6-12/h4-5,8,13H,2-3,6-7,12H2,1H3
InChIKey
ANIBJVLRYPKMKX-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Nitric-oxide synthase, brain Target Info Inhibitor [534663]
BioCyc Pathway Citrulline-nitric oxide cycle
KEGG Pathway Arginine and proline metabolism
Metabolic pathways
Calcium signaling pathway
Phagosome
Circadian entrainment
Long-term depression
Salivary secretion
Alzheimer's disease
Amyotrophic lateral sclerosis (ALS)
NetPath Pathway EGFR1 Signaling Pathway
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Arginine and Proline Metabolism
Reactome ROS production in response to bacteria
Nitric oxide stimulates guanylate cyclase
WikiPathways Monoamine Transport
Myometrial Relaxation and Contraction Pathways
Amyotrophic lateral sclerosis (ALS)
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
Spinal Cord Injury
Alzheimers Disease
Effects of Nitric Oxide
Serotonin Transporter Activity
References
Ref 534663J Med Chem. 1998 Jul 2;41(14):2636-42.Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase.
Ref 534663J Med Chem. 1998 Jul 2;41(14):2636-42.Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase.

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