Drug Information

Drug General Information
Drug ID
D0J3AV
Former ID
DIB010202
Drug Name
PEG-LPA-2
Synonyms
Leptin receptor antagonists (cancer/endometriosis); PEG-LPA-2; Leptin receptor antagonists (cancer/endometriosis), CRT; Leptin receptor antagonists (cancer/endometriosis), Cancer Research Technology; PEGylated leptin receptor antagonists (cancer/endometriosis), CRT; PEGylated leptin receptor antagonists (cancer/endometriosis), Cancer Research Technology
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Investigative [543464]
Company
Boston Biomedical Research Inst
Target and Pathway
Target(s) Leptin receptor Target Info Antagonist [543464]
KEGG Pathway Cytokine-cytokine receptor interaction
Neuroactive ligand-receptor interaction
AMPK signaling pathway
Jak-STAT signaling pathway
Adipocytokine signaling pathway
Non-alcoholic fatty liver disease (NAFLD)
Pathway Interaction Database Signaling events mediated by PTP1B
WikiPathways Leptin signaling pathway
AMPK Signaling
References
Ref 543464(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).
Ref 543464(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1712).

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