Drug General Information
Drug ID
D0J4EG
Former ID
DIB007485
Drug Name
L-648051
Drug Type
Small molecular drug
Indication Asthma [ICD10:J45] Terminated [544545]
Company
Merck & Co Inc
Structure
Download
2D MOL

3D MOL

Formula
C24H28O8S
Canonical SMILES
S(=O)(=O)(c1ccc(C(=O)CCC(=O)O)cc1)CCCOc1c(c(c(cc1)C(=O)<br />C)O)CCC
CAS Number
CAS 91541-18-3
PubChem Compound ID
Target and Pathway
Target(s) Cysteinyl leukotriene receptor 1 Target Info Modulator
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
NetPath Pathway TGF_beta_Receptor Signaling Pathway
IL4 Signaling Pathway
IL3 Signaling Pathway
Pathway Interaction Database Endothelins
Reactome Leukotriene receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 544545Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000103)

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