Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J4FE
|
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| Former ID |
DIB019428
|
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| Drug Name |
compound 3
|
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| Drug Type |
Small molecular drug
|
||||
| Formula |
C18H16N2O3
|
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| InChI |
InChI=1S/C18H16N2O3/c1-11-6-8-12(9-7-11)19-17(21)18-10-14(18)16(20-22)13-4-2-3-5-15(13)23-18/h2-9,14,22H,10H2,1H3,(H,19,21)/b20-16-
|
||||
| InChIKey |
VKCTUZKPBYSTDW-SILNSSARSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Metabotropic glutamate receptor 2 | Target Info | Modulator (allosteric modulator) | [531276] | |
| Metabotropic glutamate receptor3 | Target Info | Modulator (allosteric modulator) | [531276] | ||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Ionotropic glutamate receptor pathway | |||||
| Metabotropic glutamate receptor group II pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Metabotropic glutamate receptor group II pathway | |||||
| References | |||||
| Ref 531276 | Chemical switch of a metabotropic glutamate receptor 2 silent allosteric modulator into dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulators. J Med Chem. 2010 Dec 23;53(24):8775-9. | ||||
| Ref 541393 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6223). | ||||
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