Drug General Information
Drug ID	D0J4PB
Former ID	DIB010834
Drug Name	GW 597599
Indication	Mood disorder [ICD10:F30-F39]		Phase 2	[547359]
Company	GlaxoSmithKline
Structure		Download 2D MOL
Target and Pathway
Target(s)	Substance-P receptor	Target Info	Antagonist	[530964]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Measles
PANTHER Pathway	CCKR signaling map ST
Reactome	G alpha (q) signalling events
WikiPathways	SIDS Susceptibility Pathways
	Gastrin-CREB signalling pathway via PKC and MAPK
	Spinal Cord Injury
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 547359	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015473)
Ref 530964	Application of LC-NMR to the identification of bulk drug impurities in NK1 antagonist GW597599 (vestipitant). Magn Reson Chem. 2010 Jul;48(7):523-30.

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