Drug General Information
Drug ID
D0J4PM
Former ID
DIB009531
Drug Name
NNC-0151-0000-0000
Synonyms
Neutrazumab; NN-8209; Anti-C5aR monoclonal antibodies (rheumatoid arthritis/SLE), G2/Novo Nordisk
Drug Type
Antibody
Indication Rheumatoid arthritis [ICD9: 710-719, 714; ICD10:M05-M06] Phase 2 [529141]
Company
G2 Therapies Ltd
Target and Pathway
Target(s) Complement C5 Target Info [529141]
KEGG Pathway Complement and coagulation cascades
Prion diseases
Pertussis
Staphylococcus aureus infection
Herpes simplex infection
Systemic lupus erythematosus
Reactome Activation of C3 and C5
Peptide ligand-binding receptors
G alpha (i) signalling events
Regulation of Complement cascade
WikiPathways Complement Activation, Classical Pathway
Human Complement System
Spinal Cord Injury
Allograft Rejection
GPCR ligand binding
GPCR downstream signaling
Complement cascade
References
Ref 529141Complement-targeted therapeutics. Nat Biotechnol. 2007 Nov;25(11):1265-75.
Ref 529141Complement-targeted therapeutics. Nat Biotechnol. 2007 Nov;25(11):1265-75.

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