TTD | Drug: D0J7OM

Drug General Information
Drug ID	D0J7OM
Former ID	DNC008099
Drug Name	6-(benzylamino)-9-butyl-9H-purine-2-carbonitrile
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529240]
Structure		Download 2D MOL 3D MOL
Formula	C17H18N6
Canonical SMILES	CCCCN1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)C#N
InChI	1S/C17H18N6/c1-2-3-9-23-12-20-15-16(21-14(10-18)22-17(15)23)19-11-13-7-5-4-6-8-13/h4-8,12H,2-3,9,11H2,1H3,(H,19,21,22)
InChIKey	OJVVVZACBFLFEJ-UHFFFAOYSA-N
PubChem Compound ID	24777047
Target and Pathway
Target(s)	Cathepsin L	Target Info	Inhibitor	[529240]
KEGG Pathway	Lysosome
	Phagosome
	Antigen processing and presentation
	Proteoglycans in cancer
	Rheumatoid arthritis
NetPath Pathway	IL4 Signaling Pathway
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
Reactome	Endosomal/Vacuolar pathway
	Collagen degradation
	Degradation of the extracellular matrix
	Trafficking and processing of endosomal TLR
	Assembly of collagen fibrils and other multimeric structures
	MHC class II antigen presentation
WikiPathways	Primary Focal Segmental Glomerulosclerosis FSGS
References
Ref 529240	J Med Chem. 2008 Feb 14;51(3):545-52. Epub 2008 Jan 4.Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.
Ref 529240	J Med Chem. 2008 Feb 14;51(3):545-52. Epub 2008 Jan 4.Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

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Drug Information