Drug Information

Drug General Information
Drug ID
D0J9UB
Former ID
DNCL002463
Drug Name
RG7593
Indication Hematological malignancies [ICD9: 200-209; ICD10:C81-C86] Discontinued in Phase 2 [548683]
Company
Seattle Genetics; Roche
Target and Pathway
Target(s) B-cell receptor CD22 Target Info Modulator [551601]
KEGG Pathway Cell adhesion molecules (CAMs)
Hematopoietic cell lineage
B cell receptor signaling pathway
PANTHER Pathway B cell activation
Pathway Interaction Database BCR signaling pathway
Reactome Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
WikiPathways B Cell Receptor Signaling Pathway
References
Ref 548683Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027651)
Ref 551601Clinical pipeline report, company report or official report of Roche.

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