Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0JH6W
|
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| Former ID |
DNC000585
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| Drug Name |
DX-9065a
|
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| Drug Type |
Small molecular drug
|
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| Indication | Angina pectoris [ICD9: 413; ICD10:I20] | Discontinued in Phase 2 | [545649] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C26H39ClN4O8
|
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| Canonical SMILES |
CC(=N)N1CCC(C1)OC2=CC=C(C=C2)C(CC3=CC4=C(C=C3)C=CC(=C4)<br />C(=N)N)C(=O)O.O.O.O.O.O.Cl
|
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| InChI |
1S/C26H28N4O3.ClH.5H2O/c1-16(27)30-11-10-23(15-30)33-22-8-6-19(7-9-22)24(26(31)32)13-17-2-3-18-4-5-20(25(28)29)14-21(18)12-17;;;;;;/h2-9,12,14,23-24,27H,10-11,13,15H2,1H3,(H3,28,29)(H,31,32);1H;5*1H2/t23-,24-;;;;;;/m0....../s1
|
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| InChIKey |
LJCBAPRMNYSDOP-LVCYMWGESA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Coagulation factor Xa | Target Info | Inhibitor | [535685] | |
| KEGG Pathway | Complement and coagulation cascades | ||||
| PANTHER Pathway | Blood coagulation | ||||
| Pathway Interaction Database | Beta2 integrin cell surface interactions | ||||
| PathWhiz Pathway | Coagulation | ||||
| Reactome | Extrinsic Pathway of Fibrin Clot Formation | ||||
| Intrinsic Pathway of Fibrin Clot Formation | |||||
| Common Pathway of Fibrin Clot Formation | |||||
| Gamma-carboxylation of protein precursors | |||||
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | |||||
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | |||||
| References | |||||
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