Drug General Information
Drug ID	D0JI1J
Former ID	DIB009306
Drug Name	GP-683
Synonyms	Analgesic-sparing agent, Univ Texas
Drug Type	Small molecular drug
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Terminated	[546153]
Company	Metabasis Therapeutics Inc
Structure		Download 2D MOL 3D MOL
Formula	C23H22N4O3
Canonical SMILES	n1(c2c(c(c1)c1ccccc1)c(ncn2)Nc1ccccc1)[C@H]1[C@@H]([C@@<br />H]([C@H](O1)C)O)O
CAS Number	CAS 144928-17-6
PubChem Compound ID	5311109
Target and Pathway
Target(s)	Adenosine kinase	Target Info	Inhibitor	[534462]
BioCyc Pathway	Superpathway of purine nucleotide salvage
	Adenine and adenosine salvage II
KEGG Pathway	Purine metabolism
	Metabolic pathways
Reactome	Purine salvage
WikiPathways	Metabolism of nucleotides
References
Ref 546153	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006618)
Ref 534462	The effect of GP683, an adenosine kinase inhibitor, on the desflurane anesthetic requirement in dogs. Anesth Analg. 1997 Sep;85(3):675-80.

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