Drug Information

Drug General Information
Drug ID
D0JI8B
Former ID
DIB011595
Drug Name
Milataxel
Synonyms
M-10; MAC-321; Milataxel (oral); TL-00139; TL-139; Milataxel (oral), Taxolog; MAC-321 (injectable), Taxolog/Wyeth; MAC-321 (oral), Taxolog/Wyeth; TL-00139 (injectable), Taxolog/Wyeth; TL-00139 (oral), Taxolog/Wyeth; TL-139 (injectable), Taxolog/Wyeth; TL-139 (oral), Taxolog/Wyeth
Drug Type
Small molecular drug
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Phase 2 [522328]
Company
Taxolog Inc
Structure
Download
2D MOL

3D MOL
Formula
C44H55NO16
Canonical SMILES
[C@]12([C@@H]([C@]3([C@@H](C[C@@H]2OC(=O)CC)OC3)OC(=O)C<br />)[C@@H]([C@]2(C(C(=C([C@H](C2)OC(=O)[C@@H]([C@@H](NC(=O<br />)OC(C)(C)C)c2occc2)O)C)[C@H](C1=O)O)(C)C)O)OC(=O)c1cccc<br />c1)C
CAS Number
CAS 393101-41-2
PubChem Compound ID
44153786
Target and Pathway
Target(s) Tubulin Target Info Inhibitor [549708]
References
Ref 522328ClinicalTrials.gov (NCT00685204) An Efficacy Study of Milataxel (TL139) Administered Orally for Malignant Mesothelioma. U.S. National Institutes of Health.
Ref 549708J Clin Oncol 28, 2010 (suppl; abstr e13075).

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