Drug Information

Drug General Information
Drug ID
D0JL3O
Former ID
DNC010649
Drug Name
NICARBAZIN
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530469]
Structure
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2D MOL

3D MOL
Formula
C19H18N6O6
Canonical SMILES
CC1=CC(=NC(=O)N1)C.C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)[N+]<br />(=O)[O-])[N+](=O)[O-]
InChI
1S/C13H10N4O5.C6H8N2O/c18-13(14-9-1-5-11(6-2-9)16(19)20)15-10-3-7-12(8-4-10)17(21)22;1-4-3-5(2)8-6(9)7-4/h1-8H,(H2,14,15,18);3H,1-2H3,(H,7,8,9)
InChIKey
UKHWDRMMMYWSFL-UHFFFAOYSA-N
PubChem Compound ID
9507
Target and Pathway
Target(s) Fatty-acid amide hydrolase Target Info Inhibitor [530469]
BioCyc Pathway Anandamide degradation
KEGG Pathway Retrograde endocannabinoid signaling
PANTHER Pathway Anandamide degradation
References
Ref 530469Bioorg Med Chem Lett. 2009 Dec 1;19(23):6793-6. Epub 2009 Sep 30.Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.
Ref 530469Bioorg Med Chem Lett. 2009 Dec 1;19(23):6793-6. Epub 2009 Sep 30.Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.

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