Drug Information

Drug General Information
Drug ID
D0K0GN
Former ID
DIB004754
Drug Name
LDI-200
Synonyms
Chorionic gonadotropin, Milkhaus; HCG, Milkhaus; Oncology therapeutics, Milkhaus
Indication Leukemia [ICD9: 208.9; ICD10:C90-C95] Discontinued in Phase 3 [546170]
Company
Milkhaus Laboratory Inc
Target and Pathway
Target(s) Lutropin-choriogonadotropic hormone receptor Target Info Modulator [543644]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Ovarian steroidogenesis
Prolactin signaling pathway
NetPath Pathway FSH Signaling Pathway
Pathway Interaction Database Arf6 signaling events
PathWhiz Pathway Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin
Reactome Hormone ligand-binding receptors
G alpha (s) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Ovarian Infertility Genes
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 546170Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006739)
Ref 543644(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 254).

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