TTD | Drug: D0K1MS

Drug General Information
Drug ID	D0K1MS
Former ID	DNC014627
Drug Name	2-Methoxy-5-(5,6,7-trimethoxy-indan-1-yl)-phenol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[525450]
Structure		Download 2D MOL 3D MOL
Formula	C19H22O5
Canonical SMILES	COC1=C(C=C(C=C1)C2CCC3=CC(=C(C(=C23)OC)OC)OC)O
InChI	1S/C19H22O5/c1-21-15-8-6-11(9-14(15)20)13-7-5-12-10-16(22-2)18(23-3)19(24-4)17(12)13/h6,8-10,13,20H,5,7H2,1-4H3
InChIKey	QYUAUFKQRRPTIK-UHFFFAOYSA-N
PubChem Compound ID	10336746
Target and Pathway
Target(s)	Tubulin	Target Info	Inhibitor	[525450]
Target(s)	Tubulin beta	Target Info	Inhibitor	[525450]
KEGG Pathway	Phagosome
	Gap junction
	Pathogenic Escherichia coli infection
NetPath Pathway	FSH Signaling Pathway
	TCR Signaling Pathway
	EGFR1 Signaling Pathway
PANTHER Pathway	Cytoskeletal regulation by Rho GTPase
PANTHER Pathway	Huntington disease
Reactome	Regulation of PLK1 Activity at G2/M Transition
	Loss of Nlp from mitotic centrosomes
	Recruitment of mitotic centrosome proteins and complexes
	Loss of proteins required for interphase microtubule organization?from the centrosome
	Anchoring of the basal body to the plasma membrane
WikiPathways	Parkin-Ubiquitin Proteasomal System pathway
	Pathogenic Escherichia coli infection
	Mitotic G2-G2/M phases
References
Ref 525450	Bioorg Med Chem Lett. 1999 Feb 8;9(3):407-12.The synthesis and evaluation of temperature sensitive tubulin toxins.
Ref 525450	Bioorg Med Chem Lett. 1999 Feb 8;9(3):407-12.The synthesis and evaluation of temperature sensitive tubulin toxins.

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Drug Information